Bacalini_sampleSheet.RdDescription file for samples in Bacalini data set (Bacalini et al. 2015) . 87 samples have a family-based structure with a Down syndrome patient, a mother and one unaffected sibling coming from each of 29 included families. Thus, each sample belongs to one of three groups: Down syndrome patients (DSP), Down syndrome mothers (DSM) or Down syndrome siblings (DSS). `meNet::Bacalini_sampleSheet` is a subset of the original sample sheet which includes more details for every samples.
Bacalini_sampleSheet
A data frame with 87 rows and columns:
Unique identifier for every sample.
A group to which the sample belongs. One of DSP, DSM or DSS.
Original sample sheet was downloaded from the Gene Expression Omnibus (GEO) data repository as part of the data set with accession number GSE52588 https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE52588.
Bacalini MG, Gentilini D, Boattini A, Giampieri E, Pirazzini C, Giuliani C, Fontanesi E, Scurti M, Remondini D, Capri M, others (2015). “Identification of a DNA methylation signature in blood cells from persons with Down Syndrome.” Aging (Albany NY), 7(2), 82.